GERTEIS® Maschinen + Processengineering AG
Roller Compaction & Dry Granulation Systems
Precision Dry Granulation for Pharmaceutical Solid Dose
Gerteis is the global benchmark in roller compaction technology – purpose-built for pharmaceutical dry granulation where moisture, heat, and solvent exposure are process constraints. MHS Pharma represents Gerteis across the Northeast United States, providing direct access to the full equipment line alongside hands-on application guidance and project support.
Whether you’re developing a new solid dose formulation at lab scale or scaling a validated process to commercial production, Gerteis systems deliver the ribbon quality, granule consistency, and process control your application demands.
Why Gerteis
Consistent Process Control
Gerteis systems use a feedback control loop to maintain consistent roll gap – delivering reproducible results batch to batch with minimal process variation.
GMP-Native Design
Easy disassembly, contained product contact parts, and full audit trail capability built in – not retrofitted. Designed for regulated pharmaceutical environments from the ground up.
True Lab-to-Commercial Scalability
Process parameters developed on the MINI-PACTOR transfer directly to commercial scale – no re-validation surprises. The same roll geometry and control philosophy across the entire product range.
Containment-Ready
Gerteis systems are configured for high-potency compound handling, with contained product paths and glove port integration for OEB 4/5 applications.
Applications
Gerteis roller compactors are deployed across a broad range of pharmaceutical solid dose applications:
- Dry granulation of moisture-sensitive and heat-sensitive APIs
- High-potency compound processing (HPAPI / OEB 4–5)
- Tablet and capsule intermediate preparation
- Controlled-release and modified-release formulation development
- Process development and scale-up studies at CDMOs
- Tech transfer and commercial manufacturing validation
Equipment Range
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MINI-PACTOR® Lab-scale roller compactor for formulation development and feasibility studies. Compact footprint, full GMP capability, and direct scale-up correlation to production systems. |
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MACRO-PACTOR® Production-scale roller compaction for high-throughput solid dose manufacturing. Designed for continuous processing, containment integration, and validated commercial output. |
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ULTRA-PACTOR® High-capacity production roller compactor for large-scale commercial manufacturing. Designed for maximum throughput with full containment capability and continuous processing integration. |
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POLYGRAN® Integrated roller compaction and granulation system combining compaction and oscillating granulation in a single contained unit – reducing footprint and transfer steps. |
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MINI-POLYGRAN® Lab-scale integrated compaction and granulation in a single compact unit. Combines the MINI-PACTOR roller compaction with inline oscillating granulation – ideal for early-stage development with limited API availability. |
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Small Scale Mill A compact, manually operated laboratory milling tool designed specifically to reproduce the grinding principles of the PACTOR® roller compaction line. Processes batches from a few grams up to 50g in a single pass, delivering particle size distributions that closely match production-scale output – making it an ideal tool for first-phase R&D and dry granulate development. |
MHS Pharma – Northeast US Representative
MHS Pharma provides direct technical representation for Gerteis across the Northeast United States. We work with pharmaceutical manufacturers, CDMOs, and development organizations at every stage – from initial feasibility through commercial installation and ongoing support.
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