McFlusion
CIP, SIP & Process Cleaning Systems
Cleaning, Sanitization & Sterilization for Pharma Equipment
McFlusion specializes in complete process and equipment solutions for cleaning (CIP/COP), sanitization, and sterilization (SIP) in pharmaceutical, biopharma, vaccine, and medical device manufacturing. The company combines expertise in cGMP-regulated processes, cleaning and sterilization technologies, and regulatory/validation requirements. Operations span the USA (Twinsburg, OH), Canada (Ancaster, ON — manufacturing and warehouse), and Denmark (Roskilde).
All McFlusion CIP/SIP products share a modular hardware and software platform built on Allen-Bradley CompactLogix PLC with 12″ PC-based touchscreen HMI, full TACCT parameter control (Time, Action, Concentration, Chemistry, Temperature), recipe editing, alarm handling, and cycle reporting. Wetted parts are AISI 316L stainless steel.
MHS Pharma represents McFlusion across the Northeast United States, supporting pharmaceutical manufacturers and CDMOs with cleaning system selection, process development, and validation support for both solid dose and sterile manufacturing environments.
Why McFlusion
Full TACCT Control
Every McFlusion system provides complete control over the five critical cleaning parameters — Time, Action, Concentration, Chemistry, and Temperature. Reproducible, validated cleaning cycles with full instrumentation: level, pressure, flow, temperature, and conductivity (low and high).
Cleaning Process Expertise
McFlusion provides upfront engineering including bench-scale product removal testing and full-scale cleaning tests using McFlusion equipment in customer facilities. 3D spray modelling ensures complete coverage of equipment geometries. CIP/SIP cycle development and validation support from system design through qualification.
Portable & Centralized Options
Flexible architecture from wheeled portable units for point-of-use cleaning to centralized fixed systems for facility-wide integration. Docking stations provide standardized connection infrastructure for small-to-mid process equipment.
Data Collection & Compliance
Process Builder Design (PBD) for recipe engineering, AutoTune for cycle optimization, and DCS-GMP data collection with 24/7 raw data, event tracking, graphical playback, and remote access. Full QA documentation and electronic batch records. F₀ set points on SIP units.
Applications
McFlusion equipment serves pharmaceutical, biopharma, vaccine, and medical device manufacturing:
- CIP/SIP for blenders, granulators, fluid bed dryers, and coating pans
- Bioreactor, formulation vessel, and ultrafiltration skid cleaning and sterilization
- Aseptic fill line CIP/SIP with isolator integration
- Tablet press, spray dryer, and packaging line cleaning
- IBC, hopper, and disassembled parts washing
- Cleaning validation support for multi-product facilities
Equipment Range
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CIP Systems (MEC+) Modular clean-in-place systems for pharmaceutical and medical device manufacturing. Portable wheeled units (MEC25+, MEC35+, MEC45+) for point-of-use cleaning and fixed systems (MEC+FX1, FX2, CSV1, CSV2) for centralized facility integration. Allen-Bradley CompactLogix PLC with 12″ touchscreen HMI. Portable & fixed · Full TACCT control · 316L wetted parts · Recipe editor & cycle reporting |
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CIP/SIP Systems (Series C & S) Combined clean-in-place and sterilize-in-place systems for life science, biopharma, and vaccine manufacturing. Portable (CS10-S, CS25-S) and centralized (CSV-1, CSV-2) configurations with F₀ set points for validated sterilization. Designed for aseptic fill lines, bioreactors, formulation vessels, and freeze dryers. CIP + SIP combined · Portable & centralized · F₀ sterilization control · Docking stations available |
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SIP Systems (SS Series) Standalone sterilize-in-place systems for process equipment requiring validated sterilization. Portable (SS35-S) and wall-mount configurations. Modulating valve control with full TACCT sterilization performance, F₀ set points, and nitrogen blow-down capability. Standalone SIP · Portable & wall-mount · F₀ set points · Nitrogen blow-down |
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COP Parts Washers Specialty parts washers for clean-out-of-place washing of disassembled components, IBCs, hoppers, and process equipment. Single and double door cabinets (MEC+PW-1, PW-2, PW-3) with configurable spray systems and forced air drying. Portable cleaning racks (MEC+CR-1, CR-2) available. 1, 2 & 3 door cabinets · Configurable spray systems · Forced air drying · Portable racks |
MHS Pharma — Northeast US Representative
MHS Pharma provides direct technical representation for McFlusion across the Northeast United States. We help pharmaceutical manufacturers design and implement cleaning strategies — from initial assessment and equipment selection through cleaning validation and ongoing process optimization.
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