ChargePoint Technology
Split Butterfly Valves & Containment Solutions
Contained & Aseptic Powder Transfer
Every transfer point in a pharmaceutical process is a containment decision. ChargePoint Technology is a UK-based specialist in pharmaceutical contained powder transfer, aseptic transfer, and fluid management systems. Their patented split butterfly valve (SBV) technology, first developed in 1997, makes containment inherent to the connection itself rather than dependent on engineering controls around it: precision metal-to-metal disc seals ensure the two valve halves cannot open unless docked together, guaranteeing containment during every transfer.
ChargePoint’s SBV platform serves two distinct needs: operator protection (containment of potent compounds) and product protection (sterility assurance for aseptic manufacturing). The technology has become a pharmaceutical industry standard for high-containment powder transfers.
MHS Pharma represents ChargePoint Technology across the Northeast United States, helping pharmaceutical manufacturers and CDMOs implement contained transfer strategies from dispensing through final dosage form production.
Why ChargePoint
Proven SBV Technology
Patented split butterfly valve design with precision metal-to-metal disc seals with no elastomeric disc seals to degrade. The two halves physically cannot open unless docked together, providing an inherent containment guarantee at every transfer point. In use since 1997.
Containment Scaled to the Compound
The right containment level follows from the compound’s occupational exposure limit, not from a one-size-fits-all approach. Containment SBV achieves OEB 4 (<1 µg/m³) without extraction. Adding low-volume extraction reaches OEB 5 (<0.1 µg/m³). With the Dust Particulate Extraction System, performance extends to OEB 5+ at nanogram levels. DN50 through DN300 with DiscLock for bulk transfers.
Aseptic & Containment in One Platform
The AseptiSafe valve family provides validated sterility assurance alongside containment, protecting both the operator and the product. The AseptiSafe bio variant with H₂O₂ decontamination can reduce cleanroom classification requirements from Grade A/B to Grade D.
Single-Use & Cleaning Validation
In multi-product facilities, cleaning validation for every product-contact surface after every changeover is one of the largest operational burdens. ChargeBag (1–200 L) and ChargeBottle (2–20 L) systems bring single-use contained transfer to clinical and commercial manufacturing, eliminating the cleaning validation requirement at the transfer point entirely. Proprietary HiPure ULP7 film developed specifically for biopharma applications.
Applications
ChargePoint Technology serves pharmaceutical, biopharmaceutical, and vaccine manufacturing:
- Contained charging and discharging of process vessels, IBCs, and drums
- High-potency compound handling (HPAPI / OEB 4–5+)
- Aseptic powder transfer for fill-finish and biopharma
- Tablet press and capsule filler feeding
- API dispensing, sampling, and clinical batch manufacturing
- Retrofit containment upgrades for existing production lines
Equipment Range
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Containment Split Butterfly Valve The core ChargePoint platform for contained powder transfer of non-sterile API and formulation ingredients. Three performance tiers from OEB 4 through OEB 5+. Available with DiscLock mechanism for large-volume bulk powder transfers. Manual, sensor-assisted, or fully automatic actuation. DN50–DN300 · OEB 4 to OEB 5+ · Series 2 & Series 3 hardware · Up to 10 bar |
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AseptiSafe Aseptic split butterfly valve providing both sterility assurance and containment for sterile powder and component transfers. Sterilizable via autoclave, gamma, or SIP. The AseptiSafe bio variant adds H₂O₂ decontamination with 6-log bio-reduction, enabling use in Grade D environments instead of Grade A/B. 10⁻⁶ sterility assurance · OEB 4–5 · Autoclave, gamma, SIP, or H₂O₂ sterilization |
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ChargeBottle Rigid intermediate containers with integrated SBV connection for contained powder transfer. Available in 316L stainless steel (ChargeBottle M/MX, pressure rated to 6 bar) and HDPE (ChargeBottle P2, gamma stable). The PuroVaso square container with PuroGrab handling frame is designed for blending applications. 2–50 L · 316L stainless & HDPE · Pressure rated to 6 bar · PuroVaso for blending |
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ChargeBag Single-use containment bags with SBV interface for powder transfer. Five variants including standard PE-S, integrated single-use passive valve (PE-SBV), Quick-Fill 2D/3D for large top opening, and XL for high-volume transfers. Manufactured with proprietary HiPure ULP7 film for biopharma applications. 1–200 L · 5 variants · HiPure ULP7 film · Single & double port options |
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Single Use Passive (SUP) Disposable split butterfly valve that serves as the single-use mating half of the ChargePoint system. Eliminates cleaning validation and cross-contamination risk between batches. Gamma-sterilized and ready to use. Integrated into ChargeBag PE-SBV for a complete single-use transfer solution. DN100 · Gamma sterilized · Pairs with Series 3 Active half |
MHS Pharma — Northeast US Representative
MHS Pharma provides direct technical representation for ChargePoint Technology across the Northeast United States. We help pharmaceutical manufacturers design contained transfer strategies and select the right valve and single-use solutions for their specific process and containment requirements.
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