Contained & Aseptic Powder Transfer

ChargePoint Technology is a UK-based specialist in pharmaceutical contained powder transfer, aseptic transfer, and fluid management systems. Their patented split butterfly valve (SBV) technology — first developed in 1997 — creates a sealed environment at the point of transfer using precision metal-to-metal disc seals. The two valve halves cannot open unless docked together, guaranteeing containment during every transfer.

ChargePoint’s SBV platform serves two distinct needs: operator protection (containment of potent compounds) and product protection (sterility assurance for aseptic manufacturing). The technology has become a pharmaceutical industry standard for high-containment powder transfers.

MHS Pharma represents ChargePoint Technology across the Northeast United States, helping pharmaceutical manufacturers and CDMOs implement contained transfer strategies from dispensing through final dosage form production.

Why ChargePoint

Proven SBV Technology

Patented split butterfly valve design with precision metal-to-metal disc seals — no elastomeric disc seals to degrade. The two halves physically cannot open unless docked together, providing an inherent containment guarantee at every transfer point. In use since 1997.

Three Containment Tiers

Containment SBV achieves OEB 4 (<1 µg/m³) without extraction. Adding low-volume extraction reaches OEB 5 (<0.1 µg/m³). With the Dust Particulate Extraction System, performance extends to OEB 5+ at nanogram levels. DN50 through DN300 with DiscLock for bulk transfers.

Aseptic & Containment in One Platform

The AseptiSafe valve family provides validated sterility assurance alongside containment — protecting both the operator and the product. The AseptiSafe bio variant with H₂O₂ decontamination can reduce cleanroom classification requirements from Grade A/B to Grade D.

Single-Use Flexibility

ChargeBag (1–200 L) and ChargeBottle (2–20 L) systems bring single-use contained transfer to clinical and commercial manufacturing. Proprietary HiPure ULP7 film developed specifically for biopharma applications. Eliminates cleaning validation between batches.

Applications

ChargePoint Technology serves pharmaceutical, biopharmaceutical, and vaccine manufacturing:

  • Contained charging and discharging of process vessels, IBCs, and drums
  • High-potency compound handling (HPAPI / OEB 4–5+)
  • Aseptic powder transfer for fill-finish and biopharma
  • Tablet press and capsule filler feeding
  • API dispensing, sampling, and clinical batch manufacturing
  • Retrofit containment upgrades for existing production lines

Equipment Range

ChargePoint PharmaSafe split butterfly valve

Containment Split Butterfly Valve

The core ChargePoint platform for contained powder transfer of non-sterile API and formulation ingredients. Three performance tiers from OEB 4 through OEB 5+. Available with DiscLock mechanism for large-volume bulk powder transfers. Manual, sensor-assisted, or fully automatic actuation.

DN50–DN300 · OEB 4 to OEB 5+ · Series 2 & Series 3 hardware · Up to 10 bar

ChargePoint AseptiSafe aseptic transfer valve

AseptiSafe

Aseptic split butterfly valve providing both sterility assurance and containment for sterile powder and component transfers. Sterilizable via autoclave, gamma, or SIP. The AseptiSafe bio variant adds H₂O₂ decontamination with 6-log bio-reduction, enabling use in Grade D environments instead of Grade A/B.

10⁻⁶ sterility assurance · OEB 4–5 · Autoclave, gamma, SIP, or H₂O₂ sterilization

ChargePoint ChargeBottle rigid transfer container

ChargeBottle

Rigid intermediate containers with integrated SBV connection for contained powder transfer. Available in 316L stainless steel (ChargeBottle M/MX, pressure rated to 6 bar) and HDPE (ChargeBottle P2, gamma stable). The PuroVaso square container with PuroGrab handling frame is designed for blending applications.

2–50 L · 316L stainless & HDPE · Pressure rated to 6 bar · PuroVaso for blending

ChargePoint ChargeBag single-use transfer

ChargeBag

Single-use containment bags with SBV interface for powder transfer. Five variants including standard PE-S, integrated single-use passive valve (PE-SBV), Quick-Fill 2D/3D for large top opening, and XL for high-volume transfers. Manufactured with proprietary HiPure ULP7 film for biopharma applications.

1–200 L · 5 variants · HiPure ULP7 film · Single & double port options

ChargePoint Single Use Passive split butterfly valve

Single Use Passive (SUP)

Disposable split butterfly valve that serves as the single-use mating half of the ChargePoint system. Eliminates cleaning validation and cross-contamination risk between batches. Gamma-sterilized and ready to use. Integrated into ChargeBag PE-SBV for a complete single-use transfer solution.

DN100 · Gamma sterilized · Pairs with Series 3 Active half

MHS Pharma — Northeast US Representative

MHS Pharma provides direct technical representation for ChargePoint Technology across the Northeast United States. We help pharmaceutical manufacturers design contained transfer strategies and select the right valve and single-use solutions for their specific process and containment requirements.

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